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Continue to take naltrexone even if you feel well. Subsequent studies have suggested limited toxicity in other patient populations. You may need to stop certain opiate drugs (such as methadone) 10 to 14 days before starting naltrexone. This is to make sure you are using the medicine as it was prescribed as part of your treatment. Naltrexone may also be used for purposes not listed in this medication guide. Naltrexone will not cause you to "sober up" and will not decrease the effects of alcohol you recently consumed. It may decrease cravings for opioids after a number of weeks, and decreases the risk of overdose. Using the same amount you used before could lead to overdose or death. Take this medication by mouth with or without food, usually 50 milligrams once daily or as directed by your doctor. Subsequent studies have suggested limited toxicity in other patient populations. Before taking naltrexone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Follow your doctor's instructions very closely. Naltrexone is only part of a complete treatment program that may also include additional forms of counseling and/or monitoring. This medication blocks the effects of opiate drugs (including heroin) and similar drugs (opioids). Use this medication regularly to get the most benefit from it. Due to these reports, some physicians may check liver function tests prior to starting naltrexone, and periodically thereafter. It is important that you attend all counseling sessions, support group meetings, education programs, or other treatments recommended by your doctor. If withdrawal occurs, naltrexone should not be started. A urine test should be done to check for recent opiate drug use. Your doctor may start you at a lower dose and monitor you for any side effects or withdrawal symptoms before increasing your dose.

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