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Naltrexone will help you avoid using drugs and alcohol, but it will not prevent or relieve the withdrawal symptoms that may occur when you stop using these substances. It is used as part of a complete treatment program for drug abuse (e.g., compliance monitoring, counseling, behavioral contract, lifestyle changes). However, large doses of heroin or narcotics can overcome this block. Side effects may include trouble sleeping, anxiety, nausea, and headaches. It also decreases the desire to drink alcohol when used with a treatment program that includes counseling, support, and lifestyle changes. Follow your doctor's instructions closely. Some physicians use a naloxone challenge to determine whether an individual has any opioids remaining. Instead, naltrexone may cause or worsen withdrawal symptoms. Instead, naltrexone may cause or worsen withdrawal symptoms. It is unclear if use is safe during pregnancy. In this case, your doctor may order a higher dose (100-150 milligrams) to be taken every 2-3 days to make it easier to schedule clinic visits. It works in the brain to prevent opiate effects (e.g., feelings of well-being, pain relief). It is given once per month and has better compliance than the oral formulation. Your doctor may occasionally change your dose to make sure you get the best results. However, large doses of heroin or narcotics can overcome this block. Use naltrexone regularly to get the most benefit. Your doctor may recommend that naltrexone be given to you by a family member or other caregiver. Your doctor may start you at a lower dose and monitor you for any side effects or withdrawal symptoms before increasing your dose. Its overall benefit has been described as "modest". You should not take naltrexone if you have recently stopped using opioid medications or opioid street drugs and are now experiencing withdrawal symptoms. Your doctor may start you at a lower dose and monitor you for any side effects or withdrawal symptoms before increasing your dose.

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