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It works in the brain to prevent opiate effects (e.g., feelings of well-being, pain relief). Do not stop taking naltrexone without talking to your doctor. After stopping naltrexone treatment, you may be more sensitive to lower doses of opioids, increasing your risk of possibly life-threatening side effects from the narcotic (e.g., decreased breathing, loss of consciousness). Naltrexone may be taken with food if it upsets your stomach. Naltrexone, sold under the brand names ReVia and Vivitrol among others, is a medication primarily used to manage alcohol or opioid dependence. You may need to stop certain opiate drugs (such as methadone) 10 to 14 days before starting naltrexone. The person takes the medication about an hour (and only then) before drinking to avoid side effects that arise from chronic use. This drug passes into breast milk and may have undesirable effects on a nursing infant. Naltrexone by mouth remains an ideal treatment for a small number of people with opioid use, usually those with a stable social situation and motivation. Naltrexone may be taken with food if it upsets your stomach. It has benefits over methadone and buprenorphine in that it is not a restricted medication. This medication must not be used in people currently taking opiates, including methadone. Doing so can cause sudden withdrawal symptoms. Due to this issue, the usefulness of oral naltrexone in opioid use disorders is limited by the low retention in treatment. Naltrexone will not cause you to "sober up" and will not decrease the effects of alcohol you recently consumed. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Naltrexone by mouth remains an ideal treatment for a small number of people with opioid use, usually those with a stable social situation and motivation.

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